If traveling, you are going to want to avoid the Lloyd Expressway.

A wreck at Main St and the Lloyd Expressway has caused traffic to be backed up for the time being. Both the eastbound and westbound lanes are being shut down for the foreseeable future.

Based on several tweets and reports I've seen, there seems to be at least one fatality in the wreck. The following was posted by Evansville Watch as the accident occured:

We will keep you posted when more details become available